The Kveim test with a validated test-suspension was found to give an overall 71·9 % positive result. A very high figure was obtained among patients with hilar or. The Kveim-Siltzbach (KS) skin test has been in use worldwide for fifty years. It is a safe, simple and specific out-patient technique to confirm the diagnosis of. Kveim tests were done in forty-eight patients with Crohn’s disease. Of forty-five with definite or probable Crohn’s disease, twenty-three had a positive Kveim test.

In a series of patients, of whom were eventually found to have sarcoidosis, the intracutaneous Kveim test proved to be an important aid in the early and accurate diagnosis of sarcoidosis. The sarcoidal tissue, preferably spleen, is obtained aseptically; the suspension is heattreated and preserved with phenol.

Two patients among a group of patients with diseases other than sarcoidosis showed false-positive reactions. The widespread application of the Kveim test has been hampered by inadequate supplies of properly screened Kveim suspensions and by the need for acquiring some experience in the microscopic reading of the biopsied test-site.

The Kveim test in sarcoidosis

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Kveim-Siltzbach test revisited.

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Kveim-Siltzbach test revisited.

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